Cell and Tissue Engineering Laboratory – Bongio, Matilde

CELL AND TISSUE ENGINEERING LABORATORY

Director: Dr. Matteo Moretti

Matilde Bongio, Ph.D.

Bio

Matilde Bongio received her Ph.D. at the Department of Biomaterials (Head Professor J.A. Jansen) at the Radboud University Nijmegen Medical Center, the Netherlands, in May 2013. Her Ph.D. project focused on the biological performance both in vitro and in vivo of polymer-based injectable bone substitute materials. In 2010, she joined the Department of Bioengineering (Head Professor A.G. Mikos) at Rice University (Houston, TX, USA) to perform part of her PhD studies. Matilde joined the Cell and Tissue Laboratory in June 2013 as a Post-doc working on cellular mechanisms of bone remodelling within advanced 3D in vitro models.
Parallel to her research studies, Matilde developed a growing interest for the visual science communication, i.e. the communication of science-related topics thought visualization tools. She started to explore by her own some graphic design programs to create illustrations for her publications and presentations. Actually, it was the most enthusiastic, satisfying and relaxing part of her job where she could express her fantasy and imagination. In 2013, she began studying the charming “3D world” for biomedical applications. Matilde believes that science needs art for better understanding of things and imagination for better creative thinking. So that, in 2017, she translated her passion into a profession and she founded GoArtS, a service that provides a graphical support to researchers and clinicians, with the aim to translate scientific messages into accurate and eye-catching images.

Publications

Bersini S, Arrigoni C, Lopa S, Bongio M, Martin I, Moretti M. Engineered miniaturized models of musculoskeletal diseases. Drug Discov Today. 2016; 21(9): 1429-1436.

Bongio M*, Lopa S*, Gilardi M, Bersini S, Moretti M. A 3D vascularized bone remodeling model combining osteoblasts and osteoclasts in a CaP nanoparticle-enriched matrix. Nanomedicine (Lond). 2016; 11(9): 1073-91 (* these authors contributed equally to this work)

Arrigoni C*, Bongio M*, Talò G, et al. Rational design of prevascularized large 3D tissue constructs using computational simulations and biofabrication of geometrically controlled microvessels. Adv Healthc Mater. 2016; 5(13): 1617-26.

Lovati A, Bongio M*, Pozzi A*, Recordati C, Berzero G, Moretti M. A comparative study of diagnostic and imaging techniques for the osteoarthritis of the trapezium. Rheumatology (Oxford). 2015; 54(1): 96-103. (* these authors contributed equally to this work).

Nejadnik MR, Yang X, Bongio M, et al. Self-healing hybrid nanocomposites consisting of bisphosphonated hyaluronan and calcium phosphate nanoparticles. Biomaterials. 2014; 35(25): 6918-29.

Bongio M, Nejadnik MR, Birgani ZT, et al. In vitro and in vivo enzyme-mediated biomineralization of oligo(poly(ethylene glycol) fumarate hydrogels. Macromol Biosci. 2013; 13(6): 777-88.

Bongio M, van den Beucken JJJP, Leeuwenburgh SCG, Jansen JA Pre-clinical evaluation of injectable bone substitute materials. J Tissue Eng Regen Med. 2015; 9(3): 191-209.

Bongio M, van den Beucken JJJP, Nejadnik MR, et al. Subcutaneous tissue response and osteogenic performance of calcium phosphate nanoparticles-enriched hydrogels in the medullary cavity of guinea pigs. Acta Biomater. 2013; 9(3): 5464-74.

Bongio M, van den Beucken JJJP, Nejadnik MR, et al. Biomimetic modification of synthetic hydrogels by incorporation of adhesive peptides and calcium phosphate nanoparticles: in vitro evaluation of cell behavior. Eur Cell Mater. 2011; 22: 359-76.

Bongio M, van den Beucken JJJP, Leeuwenburgh SCG, Jansen JA. Development of bone substitute materials: from ‘biocompatible’ to ‘instructive’ J Mater Chem. 2010; 20, 8747- 8759.