1) Laboratory of Biotechnological Applications – Overview

Laboratory of Biotechnological Applications

Director: Dr. Anna Brini

OVERVIEW

Our research interest spans from the therapeutic potential of Mesenchymal Stem/ Stromal Cells (MSCs) to the genetic analysis of rare bone tumors.
In details, our research group is interested in:

• Investigating the regenerative and immunomodulatory potential of MSCs deriving from subcutaneous adipose tissue and oral tissues in appropriate preclinical models.

• Studying MSC secretome, which contains soluble factors and extracellular vesicles, for future clinical applications.

• Exploring the use of MSCs as antineoplastic drug delivery systems for the treatment of solid tumors.

• Testing innovative and clinical grade biomaterials by in vitro approaches.

• Evaluating anti-resorptive drugs effect on primary human cells.

• Identifying genetic and genomic alterations of bone tumors through Next Generation Sequencing.

• Collaborating on the management of IRCCS Galeazzi Orthopaedic Institute Biobank.