4) Zebrafish LAB – Publications

Our Publications

Use of innovative read-out system (scale) to study the mechanisms of bone function in physiological conditions, pathological models and pharmacological testing.

Carnovali M, Ottria R, Pasqualetti S, Banfi G, Ciuffreda P, Mariotti M. Effects of bioactive fatty acid amide derivatives in zebrafish scale model of bone metabolism and disease. Pharmacol Res. 2016 Feb;104:1-8.

Pasqualetti S, Banfi G, Mariotti M. Osteoblast and osteoclast behavior in zebrafish cultured scales. Cell Tissue Res. 2012 Oct;350(1):69-75.

Carnovali M, Banfi G, Mora S, Mariotti M. Tenofovir and bone: age-dependent effects in a zebrafish animal model. Antivir Ther. 2016 Apr 1.

Pasqualetti S, Congiu T., Banfi G, Mariotti M. Alendronate rescued osteoporotic phenotype in a model of glucocorticoid-induced osteoporosis in adult zebrafish scale. Int J Exp Pathol. 2015 Feb;96(1):11-20.

Pasqualetti S, Banfi G, Mariotti M. The zebrafish scale as model to study the bone mineralization process. J Mol Histol. 2012 Oct;43(5): 589-95.

 

 

Research of new compounds with effects on bone metabolism through large-scale drug screening (embryo) and small-scale drug screening (adult – scale model).

Carnovali M, Ottria R, Pasqualetti S, Banfi G, Ciuffreda P, Mariotti M. Effects of bioactive fatty acid amide derivatives in zebrafish scale model of bone metabolism and disease. Pharmacol Res. 2016 Feb;104:1-8.

Pasqualetti S, Banfi G, Mariotti M. The effects of strontium on skeletal development in zebrafish embryo. J Trace Elem Med Biol. 2013 Jun 25.

 

Creation of pathological models of human skeletal disorders in adult zebrafish (glucocorticoid-induced osteoporosis, long-bone fracture)

Pasqualetti S, Congiu T., Banfi G, Mariotti M. Alendronate rescued osteoporotic phenotype in a model of glucocorticoid-induced osteoporosis in adult zebrafish scale. Int J Exp Pathol. 2015 Feb;96(1):11-20.

 

Creation of pathological models of metabolic human diseases associated with bone complications in adult zebrafish (diabetes, obesity);

Carnovali M, Luzi L, Banfi G, Mariotti M. Chronic hyperglycemia affects bone metabolism in adult zebrafish scale model. Endocrine. 2016 Dec;54(3):808-817.

Carnovali M, Banfi G, Mariotti M. The adult zebrafish as polyhedric model for skeletal studies. J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4 Suppl 1):213-218.