Director: Dr. Massimo Mariotti
Use of innovative read-out system (scale) to study the mechanisms of bone function in physiological conditions, pathological models and pharmacological testing.
Research of new compounds with effects on bone metabolism through large-scale drug screening (embryo) and small-scale drug screening (adult – scale model)
Creation of pathological models of human skeletal disorders in adult zebrafish (glucocorticoid-induced osteoporosis, long-bone fracture)
Creation of pathological models of metabolic human diseases associated with bone complications in adult zebrafish (diabetes, obesity)