EXPERIMENTAL BIOCHEMISTRY & MOLECULAR BIOLOGY
Director: Prof. Giovanni Lombardi
Marta Gomarasca, Ph.D.
Marta Gomarasca is a post-doctoral researcher in the Laboratory of Experimental Biochemistry and Molecular Biology. She received her Master degree in Molecular Biotechnology and Bioinformatics in 2011 at Università degli Studi di Milano, Italy. She carried out her master thesis internship at Laboratory of Biomolecular Imaging, Department of Biology at Utrecht University, The Netherlands, within the Erasmus Project, where she worked on a mutagenesis approach to improve the affinity and cross-clade recognition of an HIV-1 neutralizing llama antibody (nanobody). She received her PhD in Biology at Westfälische Wilhelms-Universität Münster, Germany as a member of the Cell-in-Motion Cluster of Excellence Graduate School / International Max Plank Research School (CiM-IMPRS) joint graduate program in 2016. During her doctoral studies, she developed a drug delivery system for the intracellular delivery of cell-impermeable molecules to target intracellular pathogens such as the bacteria E. coli, Salmonella typhymurium or Shigella flexneri and the Influenza virus.
Her research activity focus on the investigation of the muscle-skeletal tissue as an endocrine organ, with particular interest on the effect of myokines on bone cells, measurement of biochemical markers of bone metabolism, cell and molecular biology and drug delivery.
Gomarasca M, Martins TFC, Greune L, Hardwidge PR, Schmidt MA, Rüter C. Bacterium-derived cell-penetrating peptides deliver gentamicin to kill intracellular pathogens. Antimicrob Agents Chemother. 2017;61(4). doi:10.1128/AAC.02545-16.